AB225. SOH26AB_0339. The effects of social deprivation on breast cancer outcomes: a retrospective cohort study
General Posters II

AB225. SOH26AB_0339. The effects of social deprivation on breast cancer outcomes: a retrospective cohort study

Claire Keohane, Ellen Barnes, Chrisen Ramkaran, Jasmine O’Callaghan, Kornelia Dembicka, Sinead Corcoran, Mohamed Ismaiel, Juliette Buckley, Anne Merrigan, Shona Tormey, Chwanrow Baban

Department of Breast Surgery, University Hospital Limerick, Limerick, Ireland

Background: Although overall breast cancer survival rates have vastly improved, there remains a limited understanding of the disparity by social deprivation. The reasons for disparities in incidence and mortality amongst different socioeconomic populations are complex and not completely understood. The aim of this retrospective cohort study is to explore the impact of social deprivation on breast cancer presentation and outcomes within a symptomatic breast unit.

Methods: A retrospective cohort study of patients with symptomatic breast cancer presenting to the regional multidisciplinary team (MDT) meeting at University Hospital Limerick was conducted. Mixed-effects logistic regression will be used to determine the association between deprivation and breast cancer outcomes. Data will be analysed using SPSS V29.0.2.0. Ethical approval was sought from the Clinical Research Ethics University Limerick (UL) Hospitals Group.

Results: Of the total population (n=446) with newly diagnosed breast cancer discussed at MDT between January 2016 and December 2017, 22.8% resided in disadvantaged, very disadvantaged, or extremely disadvantaged areas according to their Pobal deprivation index. Preliminary analysis suggests that patients presenting from disadvantaged areas are more likely to present with advanced stage or metastatic disease when compared to those from extremely affluent areas. Among patients treated with curative intent, 5-year overall survival was lower in those from socially deprived areas.

Conclusions: Patients living in more deprived areas who present with symptomatic breast cancer are more likely to present with advanced stage or metastatic disease. This suggests there are ongoing barriers to timely attendance to symptomatic breast clinics in this cohort. Age-adjusted 5-year survival was also reduced. These findings highlight the substantial impact social deprivation can have on breast cancer care and underscore the need for targeting public health interventions to reduce inequality and improve overall outcomes.

Keywords: Breast cancer; barriers; outcomes; social deprivation; survival

Acknowledgments

None.

Footnote

Funding: None.

Conflicts of Interest: The authors have no conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

doi: 10.21037/map-26-ab225
Cite this abstract as: Keohane C, Barnes E, Ramkaran C, O’Callaghan J, Dembicka K, Corcoran S, Ismaiel M, Buckley J, Merrigan A, Tormey S, Baban C. AB225. SOH26AB_0339. The effects of social deprivation on breast cancer outcomes: a retrospective cohort study. Mesentery Peritoneum 2026;10:AB225.

Article Options

Download Citation

Share