AB088. SOH26AB_0120. Outcomes and learning trends in combined colorectal and liver resections: a 12-year single-centre experience
Colorectal Session I

AB088. SOH26AB_0120. Outcomes and learning trends in combined colorectal and liver resections: a 12-year single-centre experience

David Somers1, Sean Martin1, Emir Hoti2

1Colorectal Surgery Department, St. Vincent’s University Hospital, Dublin, Ireland; 2Hepatobiliary Department, St. Vincent’s University Hospital, Dublin, Ireland

Background: Simultaneous colorectal and liver resection (CRLR) for metastatic colorectal cancer offers potential oncological benefit and remains an accepted approach for selected patients with synchronous liver metastases. This study aimed to evaluate perioperative outcomes, complication patterns, and the presence of a surgical learning trend over a 12-year period by two experienced, appropriately trained surgeons.

Methods: A prospectively maintained database of 40 patients who underwent CRLR from 2013 to 2025 was analysed. Demographic, operative, pathological, and postoperative variables were reviewed. Primary endpoints were 30- and 90-day morbidity and mortality. Secondary outcomes included length of stay (LoS) and temporal change in 30-day complications. Logistic regression adjusted for age, surgical approach, and use of adjuvant or neoadjuvant therapy.

Results: Mean age was 62.3±13.2 years. R0 resection was achieved in 95% of cases. Thirty-day morbidity occurred in 57.5% and 90-day morbidity in 15%, with no 30-day mortality. The most frequent complications were postoperative intra-abdominal collections/abscesses (33%), total parenteral nutrition (TPN) dependence (18%), and wound infection. Median LoS was 16 days. Regression analysis demonstrated a non-significant trend toward reduced 30-day morbidity over time [odds ratio (OR) =0.97 per case, P=0.12].

Conclusions: Simultaneous CRLR is safe and oncologically effective for selected patients. Although morbidity remains substantial, outcomes reflect the complexity of combined resections and align with international experience. The nonsignificant downward trend in 30-day morbidity suggests improving patient selection, perioperative care, and operative technique. Overall, CRLR is a viable strategy for synchronous metastatic colorectal cancer when performed in centres with appropriate expertise to optimize surgical and long-term clinical outcomes in this population.

Keywords: Thirty-day morbidity; 90-day morbidity; combined resection; metastatic colorectal cancer; synchronous liver metastases

Acknowledgments

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Footnote

Funding: None.

Conflicts of Interest: The authors have no conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

doi: 10.21037/map-26-ab088
Cite this abstract as: Somers D, Martin S, Hoti E. AB088. SOH26AB_0120. Outcomes and learning trends in combined colorectal and liver resections: a 12-year single-centre experience. Mesentery Peritoneum 2026;10:AB088.

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