AB144. SOH25_AB_374. The effects of social deprivation on colorectal cancer outcomes: a retrospective cohort study
Colorectal Session

AB144. SOH25_AB_374. The effects of social deprivation on colorectal cancer outcomes: a retrospective cohort study

Carolyn Cullinane, Roisin Coyne, Emma McNamara, Aaron O’Mahony, Eoghan Condon, Colin Peirce, John Calvin Coffey, Christina Fleming

Department of General and Colorectal Surgery, University Hospital Limerick, Limerick, Ireland

Background: Although colorectal cancer (CRC) survival rates are improving, there is an emerging disparity by social deprivation. The reasons for the disparities in incidence and mortality amongst different socioeconomic populations are complex and not completely understood. The aim of this study was to explore the impact of social deprivation on CRC presentation, treatment and outcomes.

Methods: We performed a retrospective cohort study of patients with CRC presenting to the regional multidisciplinary team (MDT) meeting at University Hospital Limerick. A mixed-effects logistic regression analysis approach was utilised to determine the association between deprivation and various CRC outcomes. Data was analysed using IBM SPSS V29.0.2.0. Ethical approval was sought from the Clinical Research Ethics University Limerick Hospital Group.

Results: Of the total population (n=294) with newly diagnosed CRC discussed at the MDT between January 2023 to October 2024, 18.7% (n=55) were living in disadvantaged, very disadvantaged or extremely disadvantaged areas according to their Pobal deprivation index. These patients were more likely to present with metastatic disease [odds ratio (OR) =2.7; 95% confidence interval (CI): 1.13–6.33; P=0.026] and undergo surgery as their first treatment modality (OR =2.7; 95% CI: 1.07–6.8; P=0.036). Of the 202 patients that were treated with curative intent, 18.8% (n=38) lived in socially deprived areas. Persons with a lower social deprivation score were more likely to have a stoma (OR =2.8; 95% CI: 1.06–7.06; P=0.038) and live in a direct provision facility (OR =14.7; 95% CI: 1.16–187.9; P=0.038).

Conclusions: Those living in more deprived areas face barriers to accessing timely healthcare and are more likely to present with metastatic CRC. These findings could help inform more effective targeting of public health interventions for CRC.

Keywords: Colorectal cancer (CRC); outcomes; public health; social deprivation; social inequality

Acknowledgments

None.

Footnote

Funding: None.

Conflicts of Interest: The authors have no conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

doi: 10.21037/map-25-ab144
Cite this abstract as: Cullinane C, Coyne R, McNamara E, O’Mahony A, Condon E, Peirce C, Coffey JC, Fleming C. AB144. SOH25_AB_374. The effects of social deprivation on colorectal cancer outcomes: a retrospective cohort study. Mesentery Peritoneum 2025;9:AB144.

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