AB071. SOH25_AB_081. Neutrophil to lymphocyte ratio as a prognostic marker post lower limb angioplasty
Vascular Session

AB071. SOH25_AB_081. Neutrophil to lymphocyte ratio as a prognostic marker post lower limb angioplasty

Tayyaub Mansoor1, Huda Salih1, Stewert Walsh2

1Department of Surgery, Royal College of Surgeons Ireland, Dublin, Ireland; 2Vascular Surgery Department, Galway University Hospital, Galway, Ireland

Background: Neutrophil to lymphocyte ratio (NLR) test is shown to have prognostic value in atherosclerotic disease. There is limited data on investigating its role as a prognostic indicator of re-admission in patients with peripheral vascular disease (PVD) post angioplasty. We conduct a retrospective cohort study to investigate this.

Methods: This is a retrospective cohort study conducted in Galway University Hospital from 2019–2024. Electronic hospital records were searched to identify patients. Patient data was recorded and anonymised. The neutrophil and lymphocyte ratios were calculated and analysed.

Results: A total of 81 patients were identified to have received lower limb angioplasty. Of these, 21 patients required subsequent re-admission and 60 patients did not. The mean baseline NLR of patients returning post angioplasty versus non-returning was 4.99 versus 6.71 (P=0.48). The mean post-operative NLR in the return versus non-returning cohort was 5.96 versus 6.4 (P=0.42). The calculated NLR in both return and non-returning patients was comparable in both cohorts of baseline NLR and post-NLR and therefore of no prognostic value. This is in contradiction to previous studies showing a correlation of NLR with cardiovascular outcome. A possible explanation for this result is that NLR is not a specific test and can be elevated in other disease processes. This would add a significant confounder to our results.

Conclusions: Our results show limited value of the NLR test post lower limb angioplasty in patients with PVD. Larger studies may improve statistical significance.

Keywords: Angioplasty; atherosclerosis; lower limb; neutrophil to lymphocyte ratio (NLR); peripheral vascular disease (PVD)

Acknowledgments

None.

Footnote

Funding: None.

Conflicts of Interest: The authors have no conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

doi: 10.21037/map-25-ab071
Cite this abstract as: Mansoor T, Salih H, Walsh S. AB071. SOH25_AB_081. Neutrophil to lymphocyte ratio as a prognostic marker post lower limb angioplasty. Mesentery Peritoneum 2025;9:AB071.

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