AB045. SOH25_AB_154. A single centre analysis of long-term outcomes and disease-free survival following robotic, laparoscopic and open resections of hepatocellular carcinoma (HCC)
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AB045. SOH25_AB_154. A single centre analysis of long-term outcomes and disease-free survival following robotic, laparoscopic and open resections of hepatocellular carcinoma (HCC)

Aoife Daly, Robert O’Connell, Tom Gallagher, Emir Hoti

Department of Hepatopancreaticobiliary Surgery, St. Vincent’s University Hospital, Dublin, Ireland


Background: Minimally invasive surgery is increasingly preferable to open due to reduced recovery time and peri-operative benefits. However, long-term outcomes and disease-free survival data is sparse. Prior to 2017 all hepatocellular carcinoma (HCC) resections in St. Vincent’s hospital were open, however by 2020 the majority of the cases were managed robotically. This study aims to assess disease-free survival following robotic versus laparoscopic or open resections of HCC.

Methods: A retrospective analysis was performed on all patients who underwent resections for HCC in St. Vincent’s Hospital, Dublin from 2012–2022. Data were collected using electronic patient records and clinic letters to ascertain overall rates of recurrence, further treatments and survival. The categorical data were analysed using chi-squared tests.

Results: A total of 106 patients underwent resections of HCC in St. Vincent’s Hospital between 2012–2022. In total 62% of the cases underwent open resections, 24.5% had laparoscopic resection and 13.5% had robotic resections. At time of writing, 53 participants (50%) were still alive with a 5-year overall survival of 26.9% in the laparoscopic group as compared to 19.7% in the open group (P=0.75). Median survival was 2 years in the robotic cohort (2020–2022), 4 years for laparoscopic group (2017–2021) and 3 years for the open resection group (2012–2022). Recurrence of HCC occurred in 64 participants: 71.4% in the robotic resection cohort compared to 61.5% and 57.6% in the laparoscopic and open resection cohorts respectively which was not statistically different.

Conclusions: Robotic resections are the latest treatment for HCC, conferring significant short-term benefits for the patient, but based on this data require ongoing research to demonstrate a beneficial effect in terms of survival and recurrence. Further analysis of the criteria for robotic resections as well as time to recurrence would help to further indicate whether this method results in superior outcomes for patients.

Keywords: Carcinoma; hepatocellular; laparoscopic; robotic; survival


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Funding: None.

Conflicts of Interest: The authors have no conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.


doi: 10.21037/map-25-ab045
Cite this abstract as: Daly A, O’Connell R, Gallagher T, Hoti E. AB045. SOH25_AB_154. A single centre analysis of long-term outcomes and disease-free survival following robotic, laparoscopic and open resections of hepatocellular carcinoma (HCC). Mesentery Peritoneum 2025;9:AB045.

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