AB012. SOH24AB_018. Membranous urethral length and urinary incontinence post robot assisted radical prostatectomy?—A systematic review and meta-analysis
Urology Session

AB012. SOH24AB_018. Membranous urethral length and urinary incontinence post robot assisted radical prostatectomy?—A systematic review and meta-analysis

Benjamin Mac Curtain1, Diarmaid Sugrue2, Wanyang Qian3, Michael O. Callaghan4, Niall Davis1

1Department of Urology, St Vincent’s University Hospital, Elm Park, Dublin, Ireland; 2Department of Urology, St James’ Hospital, Dublin, Ireland; 3Department of Surgery, St John of God Subiaco Hospital, Subiaco, Western Australia, Australia; 4Department of Urology, South Australia Health, Flinders Medical Centre, Bedford, South Australia, Australia

Background: To provide an update on the association between preoperative membranous urethral length (MUL) and postoperative urinary incontinence (UI) in men who undergo robot assisted radical prostatectomy (RARP)/robot assisted laparoscopic prostatectomy (RALP).

Methods: A systematic review was carried out according to Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines, using PubMed, Embase, and Scopus databases. Inclusion criteria were English language full journal articles from the last five years that assessed continence using the Expanded Prostate Cancer Index Composite (EPIC). The Critical Appraisal Skills Programme (CASP) tool for retrospective cohort studies was used to evaluate study quality. A random-effects meta-analysis was performed to pool odds ratios from available studies relating to continence as a function of MUL. The Grading of Recommendations, Assessment, Development and Evaluations (GRADE) framework was used to synthesise evidence.

Results: Six studies including 970 patients reported an association between MUL and continence at 12 months. Longer MUL was associated with reduced incontinence odds at 12-months post-surgery [pooled odds ratio (OR): 0.74, 95% confidence interval (CI): 0.68–0.87, P<0.001].

Conclusions: Preoperative MUL measured on MRI is significantly associated with postoperative continence in men undergoing RARP/RALP. We recommend consideration of magnetic resonance imaging (MRI) measurement of MUL prior to RARP/RALP to guide treatment decisions in this population.

Keywords: Magnetic resonance imaging (MRI); prostate cancer; robotic assisted radical prostatectomy (RARP); urinary incontinence (UI); urology

Acknowledgments

Funding: None.

Footnote

Conflicts of Interest: The authors have no conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

doi: 10.21037/map-24-ab012
Cite this abstract as: Mac Curtain B, Sugrue D, Qian W, Callaghan MO, Davis N. AB012. SOH24AB_018. Membranous urethral length and urinary incontinence post robot assisted radical prostatectomy?—A systematic review and meta-analysis. Mesentery Peritoneum 2024;8:AB012.

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