AB155. SOH22ABS187. Invasive lobular breast cancer metastases to rectum
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AB155. SOH22ABS187. Invasive lobular breast cancer metastases to rectum

Maha Alkhattab1, Amenah Dhannoon1, Rishabh Sehgal1, Sean Hynes2, Mark Regan1

1Department of General Surgery, University Hospital Galway, Galway, Ireland; 2Department of Pathology, University Hospital Galway, Galway, Ireland

Background: Breast cancer is the most common malignancy in females. It accounts for approximately 32% of cancers in women. The life time risk associated with the condition is estimated to be 1:10. Breast cancer can metastasise primarily to the lungs, bone, liver, brain and lymph nodes. Metastatic breast cancer in the gastrointestinal tract is thought to be extremely rare. It occurs in approximately <1% of cases. Patients with metastatic breast cancer can present with isolated or multitude of symptoms including abdominal pain, nausea, vomiting, diarrhoea, constipation, ascites, etc.

Methods: We report a case of a 57-year-old female with a remote diagnosis of a left sided [PT3pn3 (8/12) M0] infiltrating ductal carcinoma and PT1 N0 M0 infiltrating ductal carcinoma of the right breast. She underwent right sided wide local excision and left sided mastectomy with axillary lymph node clearance. She then received an adjuvant chemo-radiotherapy and immunotherapy. Fifteen years after the initial diagnosis, the patient presented with a 1-week history of a variety of generalised vague symptoms including severe buttock and lower back pain, generalised lower limb lymphedema, generalised lower abdominal discomfort associated with increased fecal urge and loose bowel movements. Examination revealed significant induration along the anterior rectal wall.

Results: Computerised topography of the abdomen and pelvis demonstrated increased soft tissue induration the gluteal and pelvic area. Colposcopy brawny inflammation and thickening of the anterior rectal wall. Biopsies were taken. Histology was in keeping with metastatic carcinoma. The patient is currently receiving immunotherapy and hormonal therapy.

Conclusions: This case highlights breast cancer metastases to the gastrointestinal tract as an important differential for patients with alteration in bowel habits in the presence of a recent or a remote history of breast cancer.

Keywords: Breast cancer; rectum; lobular; metastases; case report

Acknowledgments

Funding: None.

Footnote

Conflicts of Interest: The authors have no conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

doi: 10.21037/map-22-ab155
Cite this abstract as: Alkhattab M, Dhannoon A, Sehgal R, Hynes S, Regan M. AB155. SOH22ABS187. Invasive lobular breast cancer metastases to rectum. Mesentery Peritoneum 2022;6:AB155.

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