AB289. SOH26AB_0368. Case reports of pleomorphic dermal sarcoma excision of the head and neck from the Oral and Maxillofacial Department in University Hospital Limerick

Pleomorphic dermal sarcoma (PDS) is a rare, aggressive, and malignant skin cancer that can metastasize. It is often confused with a less aggressive tumour, atypical fibroxanthoma (AFX), due to similar microscopic features. However, PDS is more aggressive and distinguished by deeper invasion into subcutaneous tissue, tumour necrosis, lymphovascular invasion, or perineural infiltration, and is shown to have 7.14% metastasis rate. According to a recently published study, there is a lack of consensus on the surgical margin of these lesions. Surgeons often prefer a surgical margin to facilitate the reconstruction of the anatomical region post-excision. There is a lack of evidence for adjuvant therapies post-excision or for the recurrence of PDS, leading to the need for re-excision at the time of presentation.