AB186. SOH26AB_0342. Risk assessment for prostate cancer in a rapid access clinic in a level 4 Irish hospital
Urology Posters

AB186. SOH26AB_0342. Risk assessment for prostate cancer in a rapid access clinic in a level 4 Irish hospital

Usama Ahmed1, Jamil Malak1, Amir Jalali2, Ciaran O’Toole2, Ayaz Khan1, Subhasis Giri1

1Department of Urology, University Hospital Limerick, Limerick, Ireland; 2School of Medicine, University of Limerick, Limerick, Ireland

Background: Prostate cancer risk stratification traditionally incorporates prostate-specific antigen (PSA), digital rectal examination (DRE), family history, and multiparametric magnetic resonance imaging (mpMRI). While mpMRI has become central to decision-making, its predictive ability when used alone in the Irish population remains unclear. This study aims to develop a prostate cancer risk calculator based solely on MRI parameters to support biopsy decisions in a Rapid Access Prostate Clinic (RAPC).

Methods: We retrospectively analysed men referred to the RAPC. Data being collected includes PSA level, DRE findings, family history of prostate cancer, MRI Prostate Imaging Reporting and Data System (PIRADS) score, prostate volume, and subsequent biopsy histology. Cancer detection rates will be correlated with imaging variables, Gleason grade, and International Society of Urological Pathology (ISUP) grade group. Statistical modelling will then be performed to identify MRI-only predictors.

Results: MRI variables, particularly PIRADS score and prostate volume, have previously demonstrated strong associations with biopsy-proven clinically significant prostate cancer. The data collected will be compared with existing calculators based on European populations. As such, integrating MRI parameters into a predictive model may have the potential to estimate cancer risk, with or without PSA or DRE data. Pilot data is showing promising results in predicting the risk of prostate cancer, particularly in the Irish population.

Conclusions: MRI-based parameters have the potential to predict prostate cancer risk in a rapid-access setting independently. Development of an Irish population-specific MRI-only risk calculator may support more selective biopsy decision-making, reduce unnecessary procedures, and optimise clinic workflow.

Keywords: Biopsy; magnetic resonance imaging (MRI); prostate cancer; Prostate Imaging Reporting and Data System (PIRADS); risk calculator

Acknowledgments

None.

Footnote

Funding: None.

Conflicts of Interest: The authors have no conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

doi: 10.21037/map-26-ab186
Cite this abstract as: Ahmed U, Malak J, Jalali A, O’Toole C, Khan A, Giri S. AB186. SOH26AB_0342. Risk assessment for prostate cancer in a rapid access clinic in a level 4 Irish hospital. Mesentery Peritoneum 2026;10:AB186.

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