AB035. SOH26AB_0439. Rates of complications amongst peripherally inserted central catheters in paediatric populations: a systematic review and meta-analysis
Paediatrics Session

AB035. SOH26AB_0439. Rates of complications amongst peripherally inserted central catheters in paediatric populations: a systematic review and meta-analysis

Avinash Deshwal1, Michael Duffy2, Benjamin Mac Curtain3, Hassan Mahmood4

1Department of Vascular Surgery, Beaumont Hospital, Dublin, Ireland; 2Department of Cardiology, Tallaght University Hospital, Dublin, Ireland; 3Department of Urology, University Hospital Waterford, Waterford, Ireland; 4Department of Radiology, University Hospital Galway, Galway, Ireland

Background: Peripherally inserted central catheters (PICC) have become a mainstay of treatment for a broad range of indications in both adult and paediatric populations. Despite their broad range of applications, there has been an overall lack of analysis of the rates of complications associated with their use in paediatric populations. The aim of this study was to determine rates of complications after PICC in paediatric populations.

Methods: We conducted a systematic review and meta-analysis to estimate the rate of PICC-associated complications in paediatric populations excluding neonates. We searched published literature for records discussing PICC use in paediatric populations. Statistical analysis was performed using Stata 17. We calculated pooled estimates using a 95% confidence interval (CI) using a random effects model, and heterogeneity was assessed using I2.

Results: Of the 3,689 patients, there was a pooled complication rate of 6% (95% CI: 5–6%; I2=0). Rates of infections were estimated at 3% (95% CI: 3–4%; I2=0), thromboembolic complications at 1% (95% CI: 0–1%; I2=0), mechanical failures at 8% (95% CI: 7–9%; I2=0) and superficial thrombophlebitis at 1% (95% CI: 0–1%; I2=0).

Conclusions: Our findings indicate that complications associated with PICC use in paediatric populations are broadly similar to those observed in the general population, with a notably lower incidence of thrombosis. We aim to add to the growing body of literature in this area and hope to improve the overall surveillance and knowledge of PICC-related complications in paediatric populations.

Keywords: Complications; peripherally inserted central catheters (PICC); thromboembolism; infection

Acknowledgments

None.

Footnote

Funding: None.

Conflicts of Interest: The authors have no conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

doi: 10.21037/map-26-ab035
Cite this abstract as: Deshwal A, Duffy M, Curtain BM, Mahmood H. AB035. SOH26AB_0439. Rates of complications amongst peripherally inserted central catheters in paediatric populations: a systematic review and meta-analysis. Mesentery Peritoneum 2026;10:AB035.

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