AB181. SOH25_AB_158. Patterns and predictors of local breast cancer recurrence: an institutional review
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AB181. SOH25_AB_158. Patterns and predictors of local breast cancer recurrence: an institutional review

Muhammad Javid, Anne Merrigan, Shona Tormey, Juliette Buckley, Chwanrow Baban

Department of Surgery, University Hospital Limerick, Limerick, Ireland

Background: Understanding the patterns and predictors of local breast cancer recurrence is crucial for enhancing patient care and tailoring follow-up strategies. This institutional review aims to identify trends in local recurrence and significant predictive factors within a defined patient population.

Methods: A retrospective cohort study was conducted involving women diagnosed and treated for primary breast cancer at University Hospital Limerick from January 2010 to December 2023. Inclusion criteria included patients aged 18 years and older, diagnosed with stage I–III breast cancer, and having completed initial treatment. Data collection encompassed patient demographics, tumour characteristics, and location of recurrence. Kaplan-Meier survival analysis was used to estimate time to local recurrence, while Cox proportional hazards models were employed to identify significant predictors.

Results: A total of 2,892 cases were treated over a period of 14 years with 141 recurrence and 78 with metastasis. Subgroup analysis will help in determining pattern and predictor factors.

Conclusions: This review underscores that tumour characteristics and surgical margin status are pivotal in predicting local breast cancer recurrence. The study supports implementing risk-adjusted follow-up schedules and further research to optimize management strategies.

Keywords: Breast cancer; local recurrence; predictors; institutional review; risk factor

Acknowledgments

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Footnote

Funding: None.

Conflicts of Interest: The authors have no conflicts of interest to declare.

Ethical Statement: The authors are accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0/.

doi: 10.21037/map-25-ab181
Cite this abstract as: Javid M, Merrigan A, Tormey S, Buckley J, Baban C. AB181. SOH25_AB_158. Patterns and predictors of local breast cancer recurrence: an institutional review. Mesentery Peritoneum 2025;9:AB181.

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